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Total replacement of blood by an emulsion of fluorocarbon in the rat-water extravasation as a cause of failure

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Summary

After exchange transfusion by an emulsion of fluorocarbons (Fluosol 43) in rats, an increase in fluorocarbons and131I-labelled albumin was observed. These changes suggest a transfer of water from vascular to interstitial space possibly owing to the inability of the emulsion to reproduce the oncotic pressure of normal blood.

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Authors and Affiliations

  1. Pavillon Marcel Berard, Hôpital J. Courmont, F-69310, Pierre-Benite, France

    G. Fournier, V. Barrois, C. Girard, D. Robert & L. Foulletier

  2. Laboratoire de Biophysique, UER Lyon Sud Ouest, Chemin du Petit Revoyet, F-69600, Oullins, France

    G. Fournier, V. Barrois, C. Girard, D. Robert & L. Foulletier

  3. Pechiney Ugine Kuhlmann, Rue Henri Moissan, F-69310, Pierre-Benite, France

    G. Fournier, V. Barrois, C. Girard, D. Robert & L. Foulletier

Authors
  1. G. Fournier
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  2. V. Barrois
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  3. C. Girard
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  4. D. Robert
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  5. L. Foulletier
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Fournier, G., Barrois, V., Girard, C. et al. Total replacement of blood by an emulsion of fluorocarbon in the rat-water extravasation as a cause of failure. Experientia 36, 568–569 (1980). https://doi.org/10.1007/BF01965805

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  • DOI: https://doi.org/10.1007/BF01965805

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