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Experientia

, Volume 36, Issue 5, pp 568–569 | Cite as

Total replacement of blood by an emulsion of fluorocarbon in the rat-water extravasation as a cause of failure

  • G. Fournier
  • V. Barrois
  • C. Girard
  • D. Robert
  • L. Foulletier
Specialia

Summary

After exchange transfusion by an emulsion of fluorocarbons (Fluosol 43) in rats, an increase in fluorocarbons and131I-labelled albumin was observed. These changes suggest a transfer of water from vascular to interstitial space possibly owing to the inability of the emulsion to reproduce the oncotic pressure of normal blood.

Keywords

Albumin Normal Blood Interstitial Space Fluorocarbon Exchange Transfusion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    R. P. Geyer, New Engl. J. Med.289, 1077 (1973).PubMedGoogle Scholar
  2. 2.
    G. Fournier, A. Plumet, P. Felman, P. Richard, L. Foulletier, D. Vitrey and J. F. Bolot, in: Le transport de l'oxygène. Ed. Soc. réanimat. langue fr. Expans. Sci. Ed. 1976.Google Scholar
  3. 3.
    P. Felman, thesis, University of Lyon 1976.Google Scholar
  4. 4.
    L. C. Clark and S. Kaplan, 2nd Winter Fluor. Conf. St Petersburg, Florida 1974.Google Scholar
  5. 5.
    R. P. Geyer, in: Studies with Bloodless Animals, Erythrocyte Structure and Function. Alan R. Liss, Inc., New York 1975.Google Scholar
  6. 6.
    K. Yokoyama, K. Yamanouchi, M. Watanabe, T. Matsumotu, R. Murashima, T. Daimoto, T. Hamano, H. Okamoto, T. Suyama, R. Watanabe and R. Naito, Fedn Proc.34, 1478 (1975).Google Scholar
  7. 7.
    A. T. Hansen, Nature180, 504 (1961).Google Scholar
  8. 8.
    R. P. Geyer, Symp. of perfluorochem. artif. blood, p. 3. Kyoto 1975.Google Scholar

Copyright information

© Birkhäuser Verlag 1980

Authors and Affiliations

  • G. Fournier
    • 1
    • 2
    • 3
  • V. Barrois
    • 1
    • 2
    • 3
  • C. Girard
    • 1
    • 2
    • 3
  • D. Robert
    • 1
    • 2
    • 3
  • L. Foulletier
    • 1
    • 2
    • 3
  1. 1.Pavillon Marcel BerardHôpital J. CourmontPierre-Benite(France)
  2. 2.Laboratoire de BiophysiqueUER Lyon Sud Ouest, Chemin du Petit RevoyetOullins(France)
  3. 3.Pechiney Ugine KuhlmannPierre-Benite(France)

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