, Volume 36, Issue 5, pp 562–564 | Cite as

Alfalfa seeds: Effects on cholesterol metabolism

  • M. R. Malinow
  • P. McLaughlin
  • C. Stafford


Plasma cholesterol concentrations were reduced in 3 human volunteers during ingestion of diets containing alfalfa seeds (AS) for 3 weeks. No signs of toxicity were detected through serum determinations of multiple parameters. The ingestion of AS in rats decreased the concentration of plasma cholesterol, reduced intestinal absorption of exogenous and endogenous cholesterol, and increased fecal biliary excretion.


Cholesterol Toxicity Cholesterol Concentration Intestinal Absorption Plasma Cholesterol 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 2.
    F. B. Cookson, R. Altschul and S. Federoff, J. Atheroscler. Res.7, 69 (1967).PubMedGoogle Scholar
  2. 3.
    M. R. Malinow, P. McLaughlin, H. K. Naito, L. A. Lewis and W. P. McNulty, Atherosclerosis30, 27 (1978).CrossRefPubMedGoogle Scholar
  3. 4.
    M. R. Malinow, 60th Annual Meeting, Pacific Division, American Association for Advancement of Science, University of Idaho, Moscow, 3–7 June 1979, p. 30.Google Scholar
  4. 5.
    Atlas of Nutritional Data on U.S. and Canadian Feeds p. 44. Natl Acad. Sci., Washington, D.C., 1972.Google Scholar
  5. 6.
    L. L. Rudel and M. D. Morris, J. Lipid Res.14, 364 (1973).PubMedGoogle Scholar
  6. 7.
    M. Burstein, H. R. Scholnick and R. Morfin, J. Lipid Res.11, 583 (1970).PubMedGoogle Scholar
  7. 8.
    M. R. Malinow, P. McLaughlin, L. Papworth, C. Stafford, G. O. Kohler, A. L. Livingston and P. R. Cheeke, Am. J. clin. Nutr.30, 2061 (1977).PubMedGoogle Scholar
  8. 9.
    J. L. Bollman and E. Van Hook, J. appl. Physiol.24, 722 (1968).PubMedGoogle Scholar
  9. 10.
    M. R. Malinow and P. McLaughlin, Atherosclerosis15, 153 (1972).PubMedGoogle Scholar
  10. 11.
    M. R. Malinow, P. McLaughlin, C. Stafford, A. L. Livingston, G. O. Kohler and P. R. Cheeke, Am. J. clin. Nutr.32, 1810 (1979).PubMedGoogle Scholar
  11. 12.
    D. Kritchevsky and J. A. Story, Am. J. clin. Nutr.28, 305 (1975).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1980

Authors and Affiliations

  • M. R. Malinow
    • 1
    • 2
  • P. McLaughlin
    • 1
    • 2
  • C. Stafford
    • 1
    • 2
  1. 1.Oregon Regional Primate Research CenterBeavertonUSA
  2. 2.University of Oregon Health Sciences CenterPortlandUSA

Personalised recommendations