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Stimulation of macromolecular synthesis by endotoxin-treated 3T6 fibroblasts

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Summary

The interaction of endotoxin with cultured fibroblasts resulted in a depression of cellular proliferation and an increased synthesis of macromolecules, namely collagenous and non-collagenous proteins. The collagen salt-soluble fraction was increased at the expense of the insoluble fraction, and both the salt-soluble fraction and collagen secreted into the medium was underhydroxylated.

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Authors and Affiliations

  1. Temple University School of Dentistry, 3223 North Broad Street, 19140, Philadelphia, Pennsylvania, USA

    J. J. Aleo

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  1. J. J. Aleo
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Aleo, J.J. Stimulation of macromolecular synthesis by endotoxin-treated 3T6 fibroblasts. Experientia 36, 546–547 (1980). https://doi.org/10.1007/BF01965790

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