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Antiulcer activities of D-penicillamine copper complexes

  • Bioinorganic Interactions
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Abstract

A comparison of the antiulcer activities of the polymeric cuprous, cupric disulfide and mixed valence D-penicillamine copper complexes in the Shay rat are presented. The data support the conclusion that these complexes may be less toxic and more effective than the parent compound in the therapy of arthritic diseases and/or ulcers.

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Authors and Affiliations

  1. Department of Biopharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, 72205, Little Rock, Arkansas, USA

    John R. J. Sorenson, K. Ramakrishna & Thomas M. Rolniak

  2. Department of Pharmacology, College of Medicine, University of Arkansas for Medical Sciences, 72205, Little Rock, Arkansas, USA

    John R. J. Sorenson, K. Ramakrishna & Thomas M. Rolniak

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  1. John R. J. Sorenson
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  2. K. Ramakrishna
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  3. Thomas M. Rolniak
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Sorenson, J.R.J., Ramakrishna, K. & Rolniak, T.M. Antiulcer activities of D-penicillamine copper complexes. Agents and Actions 12, 408–411 (1982). https://doi.org/10.1007/BF01965411

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  • DOI: https://doi.org/10.1007/BF01965411

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