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Experientia

, Volume 28, Issue 11, pp 1324–1325 | Cite as

Die Lecithin/Lysolecithin- und Cholesterin/Cholesterinester-Beziehung im Rattenserum bei der Galaktosamin-Hepatose

  • H. Schriewer
  • H. M. Rauen
Specialia
  • 5 Downloads

Summary

After single i.p. application of 300 mg/kgd-galactosamine-hydrochloride in male conventional Wistar-II-rats, the concentration of serum cholesterol esters and serum lysolecithin decreases in statistical significance, serum lecithin increases slightly. Because the relation of esterified serum cholesterol to total serum cholesterol increases, it may be that the significant decrease of the cholesterol ester fraction, induced by the slight galactosamine-liver injury, is not only effected by transacylation-inhibition in plasma.

Literatur

  1. 1.
    D. Keppler, R. Lesch, W. Reutter undK. Decker, Expl molec. Path.9, 279 (1968).Google Scholar
  2. 2.
    R. Kattermann, R. Achelis undD. I. Wolfrum, Acta hepatosplenol.18, 153 (1971).PubMedGoogle Scholar
  3. 3.
    L. A. Carlson undB. Olhagen, J. clin. Invest.38, 854 (1959).PubMedGoogle Scholar
  4. 4.
    F. Dienstl, F. Kunz undH. A. Maizar, Klin. Wschr.44, 967 (1966).PubMedGoogle Scholar
  5. 5.
    G. Wolfram undN. Zöllner, Klin. Wschr.49, 199 (1971).PubMedGoogle Scholar
  6. 6.
    J. A. Glomset, J. Lipid. Res.9, 155 (1968).PubMedGoogle Scholar
  7. 7.
    R. Kattermann undD. I. Wolfrum, Z. klin. Chem. klin. Biochem.8, 413 (1970).PubMedGoogle Scholar
  8. 8.
    H. M. Rauen undH. Schriewer, Arzneimittel-Forsch. (Drug. Res.), im Druck.Google Scholar
  9. 9.
    L. Swell undW. D. Law, Biochim. biophys. Acta231, 302 (1971).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1972

Authors and Affiliations

  • H. Schriewer
    • 1
  • H. M. Rauen
    • 1
  1. 1.Abteilung für Experimentelle Zellforschung im Physiologisch-Chemischen Institut der Westfälischen Wilhelms-Universität MünsterMünster, WestfalenDeutschland

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