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In vitro activity of trospectomycin (U-63366F), a novel spectinomycin analog, against gram-positive isolates from cancer patients

  • New Antimicrobial Agents
  • Published:
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Abstract

The in vitro activity of trospectomycin was compared to that of amikacin, cephalothin and vancomycin against gram-positive organisms, mostly isolated from cancer patients. Trospectomycin was considerably more active than amikacin against most isolates tested, particularly species ofStaphylococcus andStreptococcus. Overall, vancomycin was the most active agent tested.

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Authors and Affiliations

  1. Section of Infectious Diseases, Department of Medical Specialties, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Box 47, 77030, Houston, Texas, USA

    K. Rolston, D. H. Ho & G. P. Bodey

Authors
  1. K. Rolston
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  2. D. H. Ho
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  3. G. P. Bodey
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Rolston, K., Ho, D.H. & Bodey, G.P. In vitro activity of trospectomycin (U-63366F), a novel spectinomycin analog, against gram-positive isolates from cancer patients. Eur. J. Clin. Microbiol. Infect. Dis. 8, 254–256 (1989). https://doi.org/10.1007/BF01965272

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  • DOI: https://doi.org/10.1007/BF01965272

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