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Effects of N-ethyl maleimide on urea facilitated transport across toad gall bladder

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Summary

An SH reactive agent, N-ethyl maleimide (10−3 M for 2 min in the luminal fluid) selectively inhibits the urea transpithelial flux across the toad gall bladder. Thiourea and antipyrine flux is not inhibited. The inhibitory effect on urea flux seems to be exerted on the carrier mechanism of urea transport.

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Authors and Affiliations

  1. Institute of General Physiology, University of Bari, 165/A, via Amendola, I-70126, Bari, Italy

    C. Ardizzone & C. Lippe

Authors
  1. C. Ardizzone
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  2. C. Lippe
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Ardizzone, C., Lippe, C. Effects of N-ethyl maleimide on urea facilitated transport across toad gall bladder. Experientia 39, 490–492 (1983). https://doi.org/10.1007/BF01965168

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  • DOI: https://doi.org/10.1007/BF01965168

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