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A histamine component in the vascular skin reactions induced by compound 48/80 in the guinea-pig

  • Abstract of Papers Given at the ‘5th Annual Meeting of the European Branch of the Histamine Club’, Paris, 6–8 May 1976
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Conclusions

Vascular skin reactions induced by compound 48/80 are ring shaped and are not homogenous. To some extent they are inhibited only by mepyramine and after low doses of compound 48/80 are resistant to burimamide.

All the above features of vascular skin reactions induced by compound 48/80 may implicate the additional release of vasoactive substances other than histamine, evoking a vasoconstriction and microcirculatory stasis, especially in the central part of the skin reaction.

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References

  1. A. Miles andE. Miles, J. Physiol.118, 228 (1952).

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  3. M. Peret, S. Andrzejewski andC. Maśliński (in preparation).

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Authors and Affiliations

  1. Department of Radiological Protection and Toxicology, Military Medical Academy, Łódź, Poland

    M. Peret & S. Andrzejewski

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  1. M. Peret
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  2. S. Andrzejewski
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Peret, M., Andrzejewski, S. A histamine component in the vascular skin reactions induced by compound 48/80 in the guinea-pig. Agents and Actions 7, 119 (1977). https://doi.org/10.1007/BF01964905

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  • DOI: https://doi.org/10.1007/BF01964905

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