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The participation of H1 and H2 histamine receptors in vascular skin permeability induced by some imidazoles

  • Abstract of Papers Given at the ‘5th Annual Meeting of the European Branch of the Histamine Club’, Paris, 6–8 May 1976
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Conclusions

The inhibitory action of both types of histamine receptor antagonists on imidazole-induced skin vascular permeability suggests that histamine receptors are involved in this phenomenon.

The mechanism of the action of imidazoles on skin vessels may be related to the endogenously released histamine [7] which subsequently stimulates its receptors and/or directs stimulation by imidazoles of both types of histamine receptors present in the vascular tree.

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Authors and Affiliations

  1. Department of Biogenic Amines, Institute of Pharmacology, Cracow, Polish Academy of Sciences, Natutowicza 60, 90-136, Łódź, Poland

    W. Kazimierczak, M. Peret, B. Adamas, A. Lewa & C. Maśliński

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  1. W. Kazimierczak
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  2. M. Peret
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  3. B. Adamas
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  4. A. Lewa
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  5. C. Maśliński
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Kazimierczak, W., Peret, M., Adamas, B. et al. The participation of H1 and H2 histamine receptors in vascular skin permeability induced by some imidazoles. Agents and Actions 7, 114 (1977). https://doi.org/10.1007/BF01964900

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  • DOI: https://doi.org/10.1007/BF01964900

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