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On the inhibitory action of DFP and PMSF on histamine release from isolated rat mast cells

  • Abstract of Papers Given at the ‘5th Annual Meeting of the European Branch of the Histamine Club’, Paris, 6–8 May 1976
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Conclusion

The present results furnish an alternative explanation to the inhibition of histamine release induced by so-called esterase inhibitors. The inhibition can well be explained on the basis that these agents inhibit metabolic energy production necessary for the coupling of stimulation to secretion in the rat mast cells.

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Authors and Affiliations

  1. Department of Pharmacology, University of Copenhagen, Copenhagen, Denmark

    B. Diamant & S. A. Patkar

Authors
  1. B. Diamant
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  2. S. A. Patkar
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Additional information

The financial support of the Danish Medical Research Council (Grant No. 512-5044) and Hesselman's Foundation, Sweden, is gratefully acknowledged.

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Diamant, B., Patkar, S.A. On the inhibitory action of DFP and PMSF on histamine release from isolated rat mast cells. Agents and Actions 7, 110–111 (1977). https://doi.org/10.1007/BF01964897

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  • DOI: https://doi.org/10.1007/BF01964897

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