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The pharmacological inhibition of the heterologous PCA reaction by histamine antagonists and chloropromazine

  • Abstract of Papers Given at the ‘5th Annual Meeting of the European Branch of the Histamine Club’, Paris, 6–8 May 1976
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Conclusion

The experiments with the passive sensitization of rat skin by mouse IgE show that this heterologous PCA reaction may be modulated (similarly to homologous reaction) by antihistaminic and antiserotonic drugs. It supports the concept of a role of both histamine and serotonin in rat and mouse anaphylaxis.

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References

  1. A. Prouvost-Danon, in:Mechanism of Allergy: Reagin Mediated Hypersensitivity (Eds. L. Goodfriend, A.H. Sehon and R.P. Orange; Marcel Dekker Inc., New York, 1973).

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Authors and Affiliations

  1. Department of Biogenic Amines, Institute of Pharmacology, Cracow Polish Academy of Sciences, Narutowicza 60, 90-136, Łódź, Poland

    U. Czerwińska, W. Kazimierczak, J. Wyczółkowska & C. Maśliński

Authors
  1. U. Czerwińska
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  2. W. Kazimierczak
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  3. J. Wyczółkowska
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  4. C. Maśliński
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Czerwińska, U., Kazimierczak, W., Wyczółkowska, J. et al. The pharmacological inhibition of the heterologous PCA reaction by histamine antagonists and chloropromazine. Agents and Actions 7, 110 (1977). https://doi.org/10.1007/BF01964896

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  • DOI: https://doi.org/10.1007/BF01964896

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