Conclusion
The increased metabolic activity was, however, observed for about an hour after the exposure of the mast cells to the releasers. The metabolic stimulation thus continued long after histamine release was completed. The persistent metabolic stimulation is likely to be related to the repair of the plasma membrane after exocytosis and restorative activities within the cell.
References
N. Chakravarty andH.J. Sørensen, Acta Physiol. Scand.91, 339 (1974).
N. Chakravarty, Exptl. Cell Res.49, 160 (1968).
T. Johansen andN. Chakravarty, Naunyn-Schmiedeberg's Arch. Pharmacol.288, 243 (1975).
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Chakravarty, N., Svendstrup, F. The time course of stimulation of glucose metabolism in mast cells in relation to histamine release, induced by antigen, dextran and compound 48/80. Agents and Actions 7, 109 (1977). https://doi.org/10.1007/BF01964895
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DOI: https://doi.org/10.1007/BF01964895