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Eosinophilic granulocyte deficiency in mice mutant insl andw loci

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Summary

HomozygousSl/Sl andW v/W v mice were found to have approximately 15% of the normal number of circulating eosinophils. Furthermore, these mice exhibited reduced numbers of eosinophilic granulocytes in the bone marrow, spleen and thymus as compared to littermate control normal mice.

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Authors and Affiliations

  1. Department of Immunology, Postgraduate Medical Center, CKP WAM, ul. Szaserów 128, 00-909, Warsaw, Poland

    W. Wiktor-Jedrzejczak & M. Ratajczak

Authors
  1. W. Wiktor-Jedrzejczak
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  2. M. Ratajczak
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Additional information

Acknowledgments. We are indebted to Dr Regina R. Skelly for comments on manuscript and to Drs Z. Pojda and C. Szczylik for fruitful discussion. This work was supported by grant 10.5 from the Polish Academy of Sciences (P.A.S.). M. Ratajczak is the recipient of a Doctoral Fellowship of P.A.S.

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Wiktor-Jedrzejczak, W., Ratajczak, M. Eosinophilic granulocyte deficiency in mice mutant insl andw loci. Experientia 41, 1596–1598 (1985). https://doi.org/10.1007/BF01964826

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