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Effect of pyrophosphate and orotidine monophosphate on cytosine deaminase regulatory properties

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The maximal velocity of the reaction (Vmax) and the half-saturation constant (K0.5) values of theS. typhimurium cytosine deaminase were altered in the presence of its effectors, pyrophosphate and orotidine monophosphate. From the kinetics of orotidine monophosphate inhibition of cytosine deaminase, it was characterized as a mixed-type noncompetitive inhibitor.

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  1. T. P. West

    Present address: Department of Biological Sciences, University of Southern Mississippi, 39406, Hattiesburg, Mississippi, USA

Authors and Affiliations

  1. Department of Biochemistry and Biophysic, Texas A & M University, 77843, College Station, Texas, USA

    T. P. West

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  1. T. P. West
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West, T.P. Effect of pyrophosphate and orotidine monophosphate on cytosine deaminase regulatory properties. Experientia 41, 1563–1564 (1985). https://doi.org/10.1007/BF01964808

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  • DOI: https://doi.org/10.1007/BF01964808

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