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Elastase digested urokinase (ED-UK)

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Elastase digested urokinase (ED-UK) was prepared from human high mol. wt urokinase (HMW-UK). It resembled low mol. wt urokinase (LMW-UK) in its mol. wt, specific activity, and active sites. The steady-state kinetic parameters of each enzyme for the activation of human Glu-plasminogen also resembled each other, as did their amidase parameters (with pyro-Glu-Gly-Arg-pNA).

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Authors and Affiliations

  1. 2nd Department of Physiology, Miyazaki Medical College, 889-16, Miyazaki, Japan

    H. Sumi & H. Mihara

  2. 2nd Department of Physiology, School of Medicine, University of the Ryukyus, 903-01, Okinawa, Japan

    T. Kosugi

  3. Biochemistry Section, Michael Reese Research Foundation, 60616, Chicago, Illinois, USA

    N. Toki

Authors
  1. H. Sumi
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  2. T. Kosugi
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  3. N. Toki
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  4. H. Mihara
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Sumi, H., Kosugi, T., Toki, N. et al. Elastase digested urokinase (ED-UK). Experientia 41, 1546–1548 (1985). https://doi.org/10.1007/BF01964799

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