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Role of gamma interferon inToxoplasma gondii infection

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Abstract

Toxoplasma gondii has emerged as an important pathogen in the ever increasing numbers of patients with disorders of the immune system. Better understanding of the mechanisms of resistance of the host against this protozoan is important for development of safe, effective alternative treatment regimens for toxoplasmosis. Gamma interferon is the cytokine that plays a central role in protection againstToxoplasma gondii. The purpose of this review is to highlight the current knowledge of the role of gamma interferon inToxoplasma gondii infection.

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Authors and Affiliations

  1. Department of Immunology and Infectious Diseases, Research Institute, Palo Alto Medical Foundation, 860 Bryant St., 94301, Palo Alto, California, USA

    C. S. Subauste & J. S. Remington

  2. Department of Medicine, Division of Infectious Diseases, Stanford University School of Medicine, Stanford, California, USA

    C. S. Subauste & J. S. Remington

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Subauste, C.S., Remington, J.S. Role of gamma interferon inToxoplasma gondii infection. Eur. J. Clin. Microbiol. Infect. Dis. 10, 58–67 (1991). https://doi.org/10.1007/BF01964408

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