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Comparison of rat, mouse, guinea-pig and human slow reacting substance of anaphylaxis (SRS-A)

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Summary

Slow reacting substance of anaphylaxis obtained from rat, mouse, guinea-pig and human tissues have exhibited similar biological activity and have reacted in the same way to chemical and enzymatic treatments. It is concluded that they appear to be the same substance or a similar class of compounds.

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Author notes

  1. P. Sirois

    Present address: Dépt. Pédiatrie, Faculté de Médecine, Centre Hospitalier Universitaire, Université de Sherbrooke, Sherbrooke, Que., Canada

Authors and Affiliations

  1. Department of Pharmacology, Royal College of Surgeons of England, London, England

    P. Sirois, D. M. Engineer, P. J. Piper & E. G. Moore

  2. Department of Immunology, The Hospital for Sick Children, Toronto, Canada

    P. Sirois, D. M. Engineer, P. J. Piper & E. G. Moore

Authors
  1. P. Sirois
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  2. D. M. Engineer
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  3. P. J. Piper
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  4. E. G. Moore
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Additional information

Acknowledgments. The authors are grateful to Le Conseil de Recherche en Santé du Québec and to Fisons Ltd for financial support. This work was also partly supported by a grant to the late Dr R. P. Orange from the Medical Research Council of Canada (MT-4605).

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Sirois, P., Engineer, D.M., Piper, P.J. et al. Comparison of rat, mouse, guinea-pig and human slow reacting substance of anaphylaxis (SRS-A). Experientia 35, 361–363 (1979). https://doi.org/10.1007/BF01964353

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  • DOI: https://doi.org/10.1007/BF01964353

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