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A specific GT1 ganglioside-luteinizing hormone interaction induces conductance changes in lipid bilayers

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Summary

A specific interaction was demonstrated between GT1 gangliosides incorporated in bilayer membranes and luteinizing hormone. This interaction would allow the penetration of a hormone subunit in the membrane. The results are discussed in terms of adenylate cyclase activation.

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Chatelain, P., Deleers, M., Poss, A. et al. A specific GT1 ganglioside-luteinizing hormone interaction induces conductance changes in lipid bilayers. Experientia 35, 334–335 (1979). https://doi.org/10.1007/BF01964335

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