Abstract
Good Clinical Practice (GCP) is a quality assurance system dealing with all stages of clinical trials which is progressively being adopted by European countries. European GCP guidelines are in preparation and will be issued soon. However, implementation of the guidelines poses major and costly problems. The training of investigators, the proper functioning of research ethics committees, the practice of obtaining written informed consent, source data verification, and quality control with internal audit and official inspections are among the most difficult issues. The obvious benefits of GCP are the improved quality of clinical trials and of data generated by such trials, as well as mutual recognition of studies conducted abroad.
Similar content being viewed by others
References
French Ministry of Health: Good clinical practice. Paris, 1987.
German Federal Ministry of Health: The principles for proper performance of the clinical investigation of drugs. Bonn, 1987.
Association of the British Pharmaceutical Industry: Guidelines on good clinical practice. PJB Publications, London, 1988.
Nordic Council on Medicine: Good clinical practice. NLN publication no. 28. Nordiska Läkemedelsnämnden, Uppsala, 1983.
Documentation of the Symposium on Good Clinical Practice in Europe, Copenhagen, 1989. Legal Studies and Services, London, 1989.
Good clinical practice in Europe. PJB Publications, London, 1989.
Documentation of the Symposium on Good Clinical Practice in Europe, Nice, 1989. Legal Studies and Service, London, 1989.
French National Assembly: Law No. 88-1138 of 20 December 1988. Journal Officiel 22 December 1988.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Regnier, B. Good clinical practice. Eur. J. Clin. Microbiol. Infect. Dis. 9, 519–522 (1990). https://doi.org/10.1007/BF01964295
Issue Date:
DOI: https://doi.org/10.1007/BF01964295