Solid phase enzyme immunoassay for detection of non-complicated cervical infection withChlamydia trachomatis

  • J. van Ulsen
  • J. H. T. Wagenvoort
  • R. V. van Eijk
  • E. Stolz
Notes

Abstract

To evaluate the usefulness of a solid phase enzyme immunoassay for diagnosis of cervical chlamydial infections, cervical smear samples from 246 women were tested using the assay and cell culture. The overall sensitivity of the assay was 67% and the specificity 92.4%. The sensitivity of the immunoassay was 54% in samples with chlamydial culture with less than 20 inclusions per slide. Thus the enzyme immunoassay failed to detect chlamydial infections in nearly half of the patients with a low amount of chlamydial antigen.

Keywords

Cell Culture Internal Medicine Enzyme Immunoassay Chlamydial Infection Cervical Infection 

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Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1988

Authors and Affiliations

  • J. van Ulsen
    • 1
  • J. H. T. Wagenvoort
    • 2
  • R. V. van Eijk
    • 3
  • E. Stolz
    • 1
  1. 1.Department of Dermato-VenereologyUniversity Hospital Rotterdam-DijkzigtRotterdamThe Netherlands
  2. 2.Department of Bacteriology and Clinical MicrobiologyUniversity Hospital Rotterdam-DijkzigtRotterdamThe Netherlands
  3. 3.National Institute of Public Health and Environmental HygieneBilthovenThe Netherlands

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