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Role of the polymorphonuclear leukocyte: Interaction with nosocomial pathogens

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References

  1. Briscoe, J. C. An experimental investigation of the phagocytic action of the alveolar cells of the lung. Journal of Pathology and Bacteriology 1908, 12: 66–100.

    Article  Google Scholar 

  2. Stillman, E. G. The presence of bacteria in the lungs of mice following inhalation. Journal of Experimental Medicine 1923, 38: 117–126.

    Article  Google Scholar 

  3. Stillman, E. G., Branch, A. Experimental production of pneumococcus pneumonia in mice by the inhalation method. Journal of Experimental Medicine 1924, 40: 733–742.

    Article  Google Scholar 

  4. Wood, W. B. Studies on the mechanism of recovery in pneumococcal pneumonia. I: The action of type specific antibody upon the pulmonary lesion of experimental pneumonia. Journal of Experimental Medicine 1941, 73: 201–222.

    Article  Google Scholar 

  5. Wood, W. B., Irons, E. N. Studies on the mechanism of recovery in pneumococcal pneumonia. II: The effect of sulfonamide therapy upon the pulmonary lesion of experimental pneumonia. Journal of Experimental Medicine 1946, 84: 365–376.

    Article  Google Scholar 

  6. Wood, W. B., McLeod, C., Iron, E. B. Studies on the mechanism of recovery in pneumonococcal pneumonia. III: Factors influencing the phagocytosis of pneumococci in the lung during sulfonamide therapy. Journal of Experimental Medicine 1946, 84: 377–386.

    Article  Google Scholar 

  7. Wood, W. B., Smith, M. R., Watson, B. Studies on the mechanism of recovery in pneumococcal pneumonia. IV: The mechanism of phagocytosis in the absence of antibody. Journal of Experimental Medicine 1946, 84: 387–402.

    Article  Google Scholar 

  8. Wood, W. B., Smith, M. R. Host-parasite relationships in experimental pneumonia due to pneumococcus type III. Journal of Experimental Medicine 1950, 92: 85–99.

    Article  PubMed  Google Scholar 

  9. Sale, L., Wood, W. B. Studies on the mechanism of recovery in pneumonia due to Friedlander's bacillus. I: Pathogenesis of experimental Friedlander's bacillus pneumonia. Journal of Experimental Medicine 1944, 86: 239–247.

    Article  Google Scholar 

  10. Loosli, C. G. The histogenesis of cells in experimental pneumonia in the dog. Journal of Experimental Medicine 1942, 75: 657–672.

    Article  Google Scholar 

  11. Loosli, C. G. The pathogenesis and pathology of experimental type I pneumococci pneumonia in the monkey. Journal of Experimental Medicine 1942, 76: 79–92.

    Article  Google Scholar 

  12. Laurenzi, G. A., Berman, L., First, M., Kass, E. H. A quantitative study of the deposition and clearance of bacteria in the murine lung. Journal of Clinical Investigation 1964, 43: 759–768.

    PubMed  Google Scholar 

  13. Green, G. M., Kass, E. H. The role of the alveolar macrophage in the clearance of bacteria from the lung. Journal of Experimental Medicine 1964, 119: 167–176.

    Article  PubMed  Google Scholar 

  14. Green, G. M., Kass, E. H. Factors influencing clearance of bacteria by the lung. Journal of Clinical Investigation 1969, 43: 769–776.

    Google Scholar 

  15. Goldstein, E., Lippert, W., Warshauer, D. Pulmonary alveolar macrophage. Defender against bacterial infection of the lung. Journal of Clinical Investigation 1974, 54: 519–528.

    PubMed  Google Scholar 

  16. Jackson, A. E., Pierce, A. K., Southern, P., Sanford, J. P. Pulmonary clearance of gram-negative bacilli. Journal of Laboratory and Clinical Medicine 1967, 69: 833–841.

    PubMed  Google Scholar 

  17. Pierce, A. K., Reynolds, R. C., Harris, G. D. Leukocytic response to inhaled bacteria. American Review of Respiratory Disease 1977, 116: 679–684.

    PubMed  Google Scholar 

  18. Toews, G. B., Gross, G. N., Perce, A. K. The relationship of inoculum size to lung bacterial clearance and phagocytic cell response in mice. American Review of Respiratory Disease 1979, 120: 559–566.

    PubMed  Google Scholar 

  19. Onofrio, J. M., Toews, G. B., Lipscomb, M. F., Pierce, A. K. Granulocyte-alveolar macrophage interaction in the pulmonary clearance ofStaphylococcus aureus. American Review of Respiratory Disease 1983, 127: 335–341.

    PubMed  Google Scholar 

  20. Dale, R. C., Reynolds, H. Y., Pennington, J. E., Elin, R. J., Pitts, T. W., Graw, R. G. Granulocyte transfusion therapy of experimentalPseudomonas pneumonia. Journal of Clinical Investigation 1974, 54: 664–671.

    PubMed  Google Scholar 

  21. Rehm, S. R., Gross, G. N., Pierce, A. K. Early bacterial clearance from murine lungs. Species dependent phagocyte response. Journal of Clinical Investigation 1980, 6: 194–199.

    Google Scholar 

  22. Toews, G. B., Vial, W. C., Hansen, E. J. Role of C5 and recruited neutrophils in early clearance of nontypableHaemophilus influenzae from murine lungs. Infection and Immunity 1985, 50: 207–212.

    PubMed  Google Scholar 

  23. Cohen, A., Batra, G., Petersen, R., Podanay, J., Nguyen, D. Size of the pool of alveolar neutrophils in normal rabbit lungs. Journal of Applied Physiology 1979, 47: 440–444.

    PubMed  Google Scholar 

  24. Vial, W. C., Toews, G. B., Perce, A. K. Early pulmonary granulocyte recruitment in response toStreptococcus pneumoniae. American Review of Respiratory Disease 1984, 129: 87–91.

    PubMed  Google Scholar 

  25. Toews, G. B., Pierce, A. K. The fifth component of complement is not required for the clearance ofStaphylococcus aureus. American Review of Respiratory Disease 1984, 129: 597–601.

    PubMed  Google Scholar 

  26. Nilsson, U. R., Muller-Eberhard, H. J. Deficiency of the fifth component of complement of mice with an inherited complement defect. Journal of Experimental Medicine 1967, 125: 1–16.

    Article  PubMed  Google Scholar 

  27. Toews, G. B., Vial, W. C. The role of C5 in polymorphonuclear leukocyte recruitment in response toStreptococcus pneumonia. American Review of Respiratory Disease 1984, 129: 82–86.

    PubMed  Google Scholar 

  28. Larsen, G. L., Mitchell, B. C., Harper, T. B., Henson, P. M. The pulmonary response of C5 sufficient and deficient mice toPseudomonas aeruginosa. American Review of Respiratory Disease 1982, 126: 306–311.

    PubMed  Google Scholar 

  29. Snyderman, R., Shin, H. S., Dannenberg, A. M. Macrophage proteinase and inflammation. The production of chemotactic activity from the fifth component of complement by macrophage proteinase. Journal of Immunology 1972, 109: 896–898.

    Google Scholar 

  30. Ward, P. A., Hill, H. J. C5 chemotactic fragments produced by an enzyme in lysosomal granules of neutrophils. Journal of Immunology 1970, 104: 535–543.

    Google Scholar 

  31. Merrill, W. W., Naegel, G. P., Mattay, R. A., Reynolds, H. Y. Alveolar macrophage-derived chemotactic factor, kinetics of in vitro production and partial characterization. Journal of Clinical Investigation 1980, 65: 268–276.

    PubMed  Google Scholar 

  32. Hunninghake, G. W., Gadek, J. E., Fales, H. M., Crystal, R. G. Human alveolar macrophage-derived chemotactic factor for neutrophils, stimuli and partial characterization. Journal of Clinical Investigation 1980, 66: 473–483.

    PubMed  Google Scholar 

  33. Valone, F. H., Franklin, M., Sun, F. F., Goetzl, E. J. Alveolar macrophage lipoxygenase products of arachidonic acid. Isolation and recognition as the predominant constituents of the neutrophil chemotactic activity elaborated by alveolar macrophages. Cellular Immunology 1980, 54: 390–401.

    Article  PubMed  Google Scholar 

  34. Fels, A. O. S., Pawlowski, N. A., Cramer, E. B., King, T. K. C., Cohn, Z. A., Scott, W. A. Human alveolar macrophages produce leukotriene B4. Proceedings of the National Academy of Sciences of the USA 1982, 79: 786–787.

    PubMed  Google Scholar 

  35. Martin, T. R., Altman, L. C., Albert, R. K., Henderson, W. R. Leukotriene B4 production by human alveolar macrophages. A potential mechanism for amplifying inflammation in the lung. American Review of Respiratory Disease 1984, 129: 106–111.

    PubMed  Google Scholar 

  36. Wessalius, L. J., Catanzaro, A., Wasserman, S. I. Neutrophil chemotactic activity generation by alveolar macrophages after bleomycin injury. American Review of Respiratory Disease 1984, 129: 485–490.

    PubMed  Google Scholar 

  37. Arnoux, B. A., Duval, D., Benveniste, J. Release of platelet activating factor from alveolar macrophages by the calcium ionophore A23187 and phagocytosis. European Journal of Clinical Investigation 1980, 10: 437–441.

    PubMed  Google Scholar 

  38. Parente, L., Fitzgerald, M., De-Nucci, G., Moncada, S. The release of lyso-platelet activating factor from guinea pig lungs. European Journal of Pharmacology 1985, 112: 281–284.

    Article  PubMed  Google Scholar 

  39. Fels, A. O. S., Cohn, Z. A. The alveolar macrophage. Journal of Applied Physiology 1986, 60: 353–369.

    PubMed  Google Scholar 

  40. Wright, D. G., Gallin, J. I. A functional differentiation of human neutrophil granules. Generation of C5a by a specific (secondary) granule product and inactivation of C5a by azurophil (primary) granule products. Journal of Immunology 1977, 119: 1068–1076.

    Google Scholar 

  41. Gallin, J. I., Wolff, S. M. Leukocyte chemotaxis. New methods for evaluation and demonstration of a cell derived chemotactic factor. Journal of Experimental Medicine 1975, 4: 567–607.

    Google Scholar 

  42. Zigmond, S. H., Hirsch, J. C. Leukocyte locomotion and chemotaxis. New methods for evaluation and demonstration of a cell derived chemotactic factor. Journal of Experimental Medicine 1973, 137: 387–410.

    Article  PubMed  Google Scholar 

  43. Phelps, P. Polymorphonuclear leukocyte motility in vitro. III: Possible release of a chemotactic substance after phagocytosis of urate crystals by polymorphonuclear luekocytes. Arthritis and Rheumatism 1969, 12: 197–204.

    PubMed  Google Scholar 

  44. Keller, H. U., Sorkin, E. Studies on chemotaxis. V: On the chemotactic effects of bacteria. International Archives of Allergy 1967, 31: 505–517.

    Google Scholar 

  45. Ward, P. A., Lepow, I. H., Newman, L. J. Bacterial factors chemotactic for polymorphonuclear leukocytes. American Journal of Pathology 1968, 52: 725–736.

    PubMed  Google Scholar 

  46. Schiffman, E., Corcoran, B. A., Wahl, S. M. N-formylmethionyl peptides as chemoattractants for leukocytes. Proceedings of the National Academy of Sciences of the USA 1975, 72: 1059–1062.

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical Center, 3916 Taubman Center, 1500 East Medical Center Drive, 48109-0360, Ann Arbor, Michigan, USA

    G. B. Toews

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Toews, G.B. Role of the polymorphonuclear leukocyte: Interaction with nosocomial pathogens. Eur. J. Clin. Microbiol. Infect. Dis. 8, 21–24 (1989). https://doi.org/10.1007/BF01964115

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