• F. Meunier
Current Topic: Review


Candida spp. are the most common fungal pathogens isolated in immunocompromised hosts, particularly cancer patients. Numerous clinical manifestations of candidiasis have been recognized, including localized infection such as oropharyngeal candidasis or focal hepatic candidiasis, and disseminated infection resulting from hematogenous spread, with or without documented fungemia. Granulocytopenic patients are particularly at risk.Candida albicans is isolated in approximately 40 % of cases of fungemia, otherCandida spp. now also commonly being isolated. The rate of morbidity and mortality secondary to candidiasis is still significant despite numerous attempts to develop better diagnostic techniques, and more effective means of chemoprophylaxis and therapy. Currently, new antifungal agents and galenic preparations of amphotericin B are being evaluated with the aim of improving the prognosis of candidiasis in immunocompromised hosts.


Cancer Patient Internal Medicine Clinical Manifestation Amphotericin Diagnostic Technique 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1989

Authors and Affiliations

  • F. Meunier
    • 1
    • 2
  1. 1.Service de Médecine et Laboratoire d'Investigation Clinique H. J. Tagnon, Clinique des Maladies Infectieuses et Laboratoire de Microbiologie, Institut Jules BordetCentre des Tumeurs de l'Université Libre de BruxellesBrusselsBelgium
  2. 2.Fund for Medical Scientific ResearchBelgium

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