Experientia

, Volume 35, Issue 10, pp 1357–1359 | Cite as

N-Acétylation enzymatique de la tryptamine par des homogénats de cerveaux deLocusta migratoria avant et après intoxication par le chlordimeform ou le lindane

  • J. -P. Allais
  • D. Gripois
  • Brigitte Moreteau
  • F. Ramade
Specialia

Enzymatic N-acetylation of tryptamine by brain homogenates ofLocusta migratoria before and after intoxication by chlordimeform or lindane

Summary

Brain homogenates ofLocusta migratoria are found to possess enzyme capable of catalyzing the N-acetylation of tryptamine. A main product of the enzymatic reaction is isolated and identified as N-acetyltryptamine by chromatography analyse. Both insecticides, chlordimeform and lindane, inhibit enzyme activity. A direct correlation between the degree of intoxication and acetylation of tryptamine is described.

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Copyright information

© Birkhäuser Verlag 1979

Authors and Affiliations

  • J. -P. Allais
    • 1
    • 2
  • D. Gripois
    • 1
    • 2
  • Brigitte Moreteau
    • 1
    • 2
  • F. Ramade
    • 1
    • 2
  1. 1.Laboratoire de ZoologieUniversité Paris-Sud, Equipe de recherche Associé au CNRS, no 227Orsay CedexFrance
  2. 2.Laboratoire d'EndocrinologieUniversité de Paris-SudOrsay CedexFrance

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