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Systemic candidiasis fromCandida albicans colonizing the gastrointestinal tract of mice

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Summary

Reproducible induction of systemicCandida infection was achieved by treating mice in whichCandida colonization had been established in the gastrointestinal tract by aminobenzylpenicillin treatment. Systemic candidiasis was induced in these mice by X-ray irradiation followed by immunosuppressive doses of dexamethasone or X-ray irradiation followed by immunosuppressive doses of trypan blue. Macrophages seem to play an important role in this systemic infection.

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References

  1. R. A. Chilgren, P. G. Quie, H. J. Meuwissen and R. Hong, Lancet2, 688 (1976).

    Google Scholar 

  2. T. Lehner, J. M. A. Wilton and L. Ivanyi, Immunology22, 775 (1972).

    CAS  PubMed  PubMed Central  Google Scholar 

  3. W. Krause, H. Matheis and K. Wulf, Lancet1, 598 (1969).

    Article  CAS  PubMed  Google Scholar 

  4. V. Fisher, Proc. Soc. exp. Biol. Med.28, 984 (1930).

    Google Scholar 

  5. T. Umenai, Tohoku J. exp. Med.126, 173 (1978).

    Article  CAS  PubMed  Google Scholar 

  6. R. M. Gorczynski, R. G. Miller and R. A. Phillips, J. exp. Med.134, 1201 (1973).

    Article  Google Scholar 

  7. A. Dimitriu, Cell. Immunol.21, 79 (1976).

    Article  CAS  PubMed  Google Scholar 

  8. M. L. Kripke, K. C. Norbury, E. Gruys and J. B. Hibbs, Infect. Immunol.17, 121 (1977).

    Article  CAS  Google Scholar 

  9. J. D. Clark, Infect. Immunol.4, 731 (1971).

    Article  CAS  Google Scholar 

  10. A. W. Phillips and E. Balish, Appl. Microbiol.14, 737 (1966).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Department of Bacteriology, Tohoku University School of Medicine, 2-1 Seiryo-machi, 980, Sendai, Japan

    T. Umenai, S. Konno & N. Ishida

Authors
  1. T. Umenai
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  2. S. Konno
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  3. N. Ishida
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Umenai, T., Konno, S. & Ishida, N. Systemic candidiasis fromCandida albicans colonizing the gastrointestinal tract of mice. Experientia 35, 1331–1332 (1979). https://doi.org/10.1007/BF01963990

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