Experientia

, Volume 35, Issue 10, pp 1329–1330 | Cite as

Changes of X-prolyl dipeptidyl-aminopeptidase activity in developing rat brain

  • T. Kato
  • T. Hama
  • T. Nagatsu
  • H. Kuzuya
  • S. Sakakibara
Specialia

Summary

We found X-prolyl dipeptidyl-aminopeptidase activity in rat brain and examined the developmental changes at various ages. The total enzyme activity per brain increased until 4 weeks of age, and then decreased during maturation. Specific activity in young rat brain was higher than that in adult rat brain. The properties of the brain enzyme were different from those of pituitary and other tissues.

Keywords

Enzyme Enzyme Activity Developmental Change Total Enzyme Total Enzyme Activity 

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Copyright information

© Birkhäuser Verlag 1979

Authors and Affiliations

  • T. Kato
    • 1
    • 2
    • 3
  • T. Hama
    • 1
    • 2
    • 3
  • T. Nagatsu
    • 1
    • 2
    • 3
  • H. Kuzuya
    • 1
    • 2
    • 3
  • S. Sakakibara
    • 1
    • 2
    • 3
  1. 1.Laboratory of Cell Physiology, Department of Life Chemistry, Graduate School at NagatsutaTokyo Institute of TechnologyYokohamaJapan
  2. 2.Department of BiochemistryTohoku Dental UniversityKoriyama, FukushimaJapan
  3. 3.Peptide InstituteProtein Research FoundationMinoh, OsakaJapan

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