Abstract
The significance of chlamydial serum IgA compared with IgM and IgG in the diagnosis of urogenital chlamydial infection was evaluated using 120 sera from different categories of patients. In urethritis patients both IgM and IgA antibodies were not found to be present consistently, whereas in patients with deep-seated chlamydial infection, IgA was more often present. Although of limited value in superficial infections, demonstration of IgA antibodies may be of value in the diagnosis of deep-seated chlamydial infections.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Schachter, J.: Biology ofChlamydia trachomatis. In: Sexually transmitted diseases. Holmes, K. K., Mårdh, P. A., Sparling, P. F., Wiesner, P. J. (ed.): McGraw-Hill, New York, 1984, p. 243–257.
Puolakkainen, M., Vesterinen, E., Purola, E., Saikku, P., Paavonen, J.: Peristence of chlamydial antibodies after pelvic inflammatory disease. Journal of Clinical Microbiology 1986, 23: 924–928.
Sarov, I., Sarov, B., Hanuka, N., Glasner, M., Kaneti, J.: The significance of serum specific IgA antibodies in diagnosis of activeChlamydia trachomatis infections. In: Oriel, D., Ridgway, G., Schachter, J., Taylor-Robinson, D., Ward, M. (ed.); Proceedings of the Sixth International Symposium on Human Chlamydial Infections. Cambridge University Press, Cambridge, 1986, p. 566–569.
Saikku, P.: Chlamydial serology. Scandinavian Journal of Infectious Diseases 1982, 14, Supplement 32: 34–37.
Cevenini, R., Rumpianesi, F., Donati, M., Sarov, I.: A rapid immunoperoxidase assay for the detection of specific antibodies toChlamydia trachomatis. Journal of Clinical Pathology 1983, 36: 353–356.
Ladany, S., Sarov, I.: Recent advances inChlamydia trachomatis. European Journal of Epidemiology 1985, 1: 235–256.
Richmond, S. J., Caul, E. O.: Fluorescent antibody studies in chlamydial infections. Journal of Clinical Microbiology 1975, 1: 345–352.
Saikku, P., Paavonen, J.: Single-antigen immunofluorescence test for chlamydial antibodies. Journal of Clinical Microbiology 1978, 8: 119–122.
Ånestad, G., Lunde, O., Moen, M., Dalaker, K.: Infertility and chlamydial infection. Fertility and Sterility 1987, 48: 787–790.
Grayston, J. T., Wang, S. P., Kuo, C. C., Campbell, L. A.: Current knowledge onChlamydia penumoniae, strain TWAR, an important cause of pneumonia and other acute respiratory diseases. European Journal of Clinical Microbiology and Infectious Diseases 1989, 8: 191–202.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Scheel, O., Ånestad, G. Significance of immunoglobulin a titres in the diagnosis of urogenital chlamydial infections. Eur. J. Clin. Microbiol. Infect. Dis. 8, 726–728 (1989). https://doi.org/10.1007/BF01963761
Issue Date:
DOI: https://doi.org/10.1007/BF01963761