Summary
Female mice that had been made estrous through hormone implantation excreted in their urine significantly enhanced levels of n-pentyl acetate,cis-2-penten-1-yl acetate, p-toluidine, 2-heptanone, and 3 unsaturated ketones. The relationship of these volatiles to a signaling function of the estrous urine is postulated. Structural elucidations of these compounds were carried out through capillary gas chromatography/mass spectrometry and the synthesis of authentic samples.
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We gratefully acknowledge support of this research by the National Institute of Child Health and Human Development (grant No. PHS RO1 HD 14889-02). Author for correspondence: M.N.
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Schwende, F.J., Wiesler, D. & Novotny, M. Volatile compounds associated with estrus in mouse urine: Potential pheromones. Experientia 40, 213–215 (1984). https://doi.org/10.1007/BF01963606
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DOI: https://doi.org/10.1007/BF01963606