Summary
Young guinea-pigs (350 g) expressed significantly greater levels of acquired resistance to challenge by larvalAmblyomma americanum ticks than older guinea-pigs (520–800 g). This finding suggests that younger guinea-pigs are immunologically more responsive to tick infestation than older mature individuals. Therefore, host age is an important variable in evaluating acquired resistance to ticks.
References
Brown, S.J., and Askenase, P.W., J. Immun.127 (1981) 2163.
Brown, S.J., Am. J. trop. Med. Hyg.31 (1982) 1285.
Brown, S.J., Graziano, F.M., and Askenase, P.W., J. Immun.129 (1982) 2407.
Brown, S.J., Galli, S.J., Gleich, G.J., and Askenase, P.W., J. Immun.129 (1982) 790.
Brown, S.J., and Askenase, P.W., Fedn Proc.42 (1983) 126.
Wikel, S.K., Ann. trop. Med. Parasit.76 (1982) 179.
Willadsen, P., Adv. Parasit.18 (1980) 293.
Brown, S.J., Bagnall, B.G., and Askenase, P.W., Exp. Parasit. (1983) in press.
Pogorelyi, A.I., Veterinaryia, Kiev6 (1966) 68.
McGowan, M.J., Camin, J.H., and McNew, P.W., J. Parasit.65 (1979) 692.
Johnston, T.H., and Bancroft, M.J., Proc. R. Soc. Qld.30 (1918) 219.
Askenase, P.W., Bagnall, B.G., and Worms, M.J., Immunology45 (1982) 501.
Trager, W., J. Parasit.25 (1939) 57.
Wikel, S.K., and Allen, J.R., Immunology30 (1976) 311.
Roberts, J.A., and Kerr, J.D., J. Parasit.62 (1976) 485.
Makinodan, T., and Kay, M.M.B., Adv. Immunol.29 (1980) 287.
Author information
Authors and Affiliations
Additional information
Supported in part by grants from the United States Public Health Service, National Institutes of Health No. AI 17555, AI 19657, RR 05443 and from the Rockefeller Foundation.
Rights and permissions
About this article
Cite this article
Brown, S.J. Effect of host age on the expression of acquired resistance to ticks. Experientia 40, 199–200 (1984). https://doi.org/10.1007/BF01963598
Issue Date:
DOI: https://doi.org/10.1007/BF01963598