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Induction of heart alterations by immunization with subcellular fractions fromCrithidia fasciculata

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Summary

Immunization of mice with subcellular fractions ofC. fasciculata led to myocarditis and electrocardiographic alterations similar to those induced by immunization withT. cruzi, the etiological agent of Chagas' disease, suggesting the presence of similar cardiotoxic antigens in both trypanosomatid flagellates.

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Authors and Affiliations

  1. Facultad de Medicina de La Plata, Centro de Investigaciones Cardiovasculares, Buenos Aires, (Argentina)

    P. M. Cabeza Meckert, J. J. Cazzulo, E. L. Segura, M. Esteva, A. M. Ruiz, R. Gelpi & R. P. Laguens

  2. INDIECH Fatala Chaben, Buenos Aires, (Argentina)

    P. M. Cabeza Meckert, J. J. Cazzulo, E. L. Segura, M. Esteva, A. M. Ruiz, R. Gelpi & R. P. Laguens

Authors
  1. P. M. Cabeza Meckert
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  2. J. J. Cazzulo
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  3. E. L. Segura
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  4. M. Esteva
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  5. A. M. Ruiz
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  6. R. Gelpi
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  7. R. P. Laguens
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Cabeza Meckert, P.M., Cazzulo, J.J., Segura, E.L. et al. Induction of heart alterations by immunization with subcellular fractions fromCrithidia fasciculata . Experientia 40, 171–173 (1984). https://doi.org/10.1007/BF01963583

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  • DOI: https://doi.org/10.1007/BF01963583

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