Polymicrobial septicemia withClostridium difficile in acute diverticulitis

  • M. Gérard
  • N. Defresne
  • P. Van der Auwera
  • F. Meunier


A case is reported of a patient without previous gastrointestinal symptoms, who presented with polymicrobial septicemia caused byEscherichia coli, Enterococcus faecalis, Clostridium difficile andBacteroides vulgatus. Septicemia occurred during acute diverticulitis. A strain ofClostridium difficile, which was of the same serogroup C as the blood culture isolate and also produced toxin, was recovered from the stools, but the pathogenic role of this organism in the gastrointestinal symptomatology was not clearly established. Other reported cases ofClostridium difficile septicemia are also reviewed.


Internal Medicine Blood Culture Diverticulitis Gastrointestinal Symptom Enterococcus Faecalis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Viscidi, R., Willey, S., Bartlett, J. G. Isolation rates and toxigenic potential ofClostridium difficile isolated from various patient populations. Gastroenterology 1981, 81: 5–9.Google Scholar
  2. 2.
    Bartlett, J. G. Antibiotic-associated pseudomembranous colitis. Reviews of Infectious Diseases 1979, 1: 530–539.Google Scholar
  3. 3.
    Spencer, R. C., Courtney, S. P., Nicol, C. D. Polymicrobial septicaemia due toClostridium difficile andBacteroides fragilis. British Medical Journal 1984, 289: 531–532.Google Scholar
  4. 4.
    Saginur, R., Fogel, R., Begin, L., Cohen, B., Mendelson, J. Splenic abscess due toClostridium difficile. Journal of Infectious Diseases 1983, 147: 1105.Google Scholar
  5. 5.
    Studemeister, A. E. Splenic abscess due toClostridium difficile andPseudomonas paucimobilis. American Journal of Medical Gastroenterology 1987, 82: 389–390.Google Scholar
  6. 6.
    Smith, L. D. S., King, E. O. Occurrence ofClostridium difficile infection in man. Journal of Bacteriology 1962, 84: 65–67.Google Scholar
  7. 7.
    Rampling, A., Warren, R. E., Bevan, P. C., Hoggarth, C. E., Swirsky, D., Hayhoe, F. G. J. Clostridium dificile in haematological malignancy. Journal of Clinical Pathology 1985, 38: 445–451.Google Scholar
  8. 8.
    Genta, V. M., Gilligan, P. H., McCarthy, L. R. Clostridium difficile. Archives of Pathology and Laboratory Medicine 1984, 108: 82–83.Google Scholar
  9. 9.
    Gérard, M., Defresne, N., Daneau, D., Van der Auwera, P., Delmee, M., Bourguignon, A. M., Meunier, F. Incidence and significance ofClostridium difficile in hospitalized cancer patients. European Journal of Clinical Microbiology and Infectious Diseases 1988, 7: 274–278.Google Scholar
  10. 10.
    Delmee, M., Homel, M., Wauters, G. Serogrouping ofClostridium difficile strains by slide agglutination. Journal of Clinical Microbiology 1985, 21: 323–324.Google Scholar
  11. 11.
    Richardson, S. A., Alcock, P. A., Gray, J. Clostridium difficile and its toxin in healthy neonates. British Medical Journal 1983, 287: 878.Google Scholar

Copyright information

© Priedr. Vieweg & Sohn Verlagsgesellschaft mbH 1989

Authors and Affiliations

  • M. Gérard
    • 1
  • N. Defresne
    • 1
  • P. Van der Auwera
    • 1
  • F. Meunier
    • 1
  1. 1.Service de Médecine Interne et Laboratoire d'Investigation Clinique H. Tagnon, Institut Jules BordetCentre des Tumeurs de l'Université Libre de BruxellesBrusselsBelgium

Personalised recommendations