, Volume 35, Issue 9, pp 1170–1171 | Cite as

GFA expression in aggregating cultures of rat C6 glioma

  • A. Bignami
  • J. Swanson
  • D. Dahl


Few C6 glioma cells synthesize the astroglia-specific GFA protein in monolayer culture. A uniform population of GFA-positive cells was obtained by aggregating C6 cells in suspension culture, as previously reported for C6 glioma maintained on sponge foam matrices. These results strongly suggest that cell-to-cell interactions promote GFA expression.


Foam Sponge Glioma Cell Suspension Culture Monolayer Culture 
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Copyright information

© Birkhäuser Verlag 1979

Authors and Affiliations

  • A. Bignami
    • 1
    • 2
  • J. Swanson
    • 1
    • 2
  • D. Dahl
    • 1
    • 2
  1. 1.Spinal Cord Injury ServiceWest Roxbury Veterans Administration Medical CenterBostonUSA
  2. 2.Department of NeuropathologyHarvard Medical SchoolBostonUSA

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