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Possible virulence marker forStreptococcus agalactiae (Lancefield group B)

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Abstract

Mouse passage of a stock strain of each of the serotypes Ia, Ib, Ia/c, II and III ofStreptococcus agalactiae was followed by increased virulence. The change was associated with an increased content of sialic acid and also with the appearance of an antigen common to all passaged strains. This antigen was subsequently detected in all but one of 12 strains isolated from infected babies or diabetic adults, but in none of 12 organisms recovered from carriers.

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References

  1. Jelinkova, J., Motlova, J. Proposed revision of nomenclature of group B streptococcus serotypes. In: Kimura, Y., Kotami, S., Shjiokawa, Y. (ed.): Recent advances in streptococci and streptococcal diseases. Reedbooks, Bracknell, 1984, p. 51–52.

    Google Scholar 

  2. Wagner, B., Kubin, U., Wagner, M., Gunter, E. Immunoelectron microscopic analysis of polysaccharide and protein surface antigens in wild strains of group B streptococci. Zentralblatt für Bakteriologie, Microbiologie und Hygiene (A) 1982, 253: 331–343.

    Google Scholar 

  3. Molinari, A., Orefici, G., Paradisi, S., Teti, G., Donelli, G., Arancia, G. Immunolocalization of capsular components on group B streptococci. Journal of Electron Microscopy 1986, 35, Supplement: 3363–3364.

    Google Scholar 

  4. Wennenstrom, D. E., Schutt, R. W. Adult mice as a model for early onset group B streptococcal disease. Infection and Immunity 1978, 19: 741–744.

    Google Scholar 

  5. Doran, T. I., Strauss, D. C., Mattingly, S. J. Factors influencing release of type III antigens by group B streptococci. Infection and Immunity 1981, 31: 615–623.

    Google Scholar 

  6. Botta, G. A. Hormonal and type-dependent adhesion of group B streptococci to human vaginal cells. Infection and Immunity 1979, 25: 1084–1086.

    Google Scholar 

  7. Shigeoka, A. O., Hall, R. T., Hill, H. R. Strain specificity of opsonin for group B streptococci types II and III. Infection and Immunity 1979, 23: 438–445.

    Google Scholar 

  8. De Paoli, P., Mucignat, G., Orefici, G., Santini, G. Influence of sialic acid contents on the chemiluminescent response of human leucocytes to group B streptococci. Microbiologica 1985, 8: 379–386.

    Google Scholar 

  9. Lancefield, R. C. A serological differentiation of specific types of bovine hemolytic streptococci (group B). Journal of Experimental Medicine 1934, 142: 165–179.

    Google Scholar 

  10. Shigeoka, A. O., Rom, N. S., Santos, J. I., Hill, H. R. Assessment of the virulence factors of group B streptococci: correlation with sialic acid content. Journal of Infectious Diseases 1983, 147: 857–863.

    Google Scholar 

  11. Lancefield, R. C. Two serological types of group B hemolytic streptococci with related, but not identical, type-specific substances. Journal of Experimental Medicine 1938, 67: 25–40.

    Google Scholar 

  12. Baker, C. J., Kasper, D. L., Davis, C. E. Immunochemical characterization of the “native” type III polysaccharide of group B streptococcus. Journal of Experimental Medicine 1976, 143: 258–270.

    Google Scholar 

  13. Kane, J. A., Karakawa, W. W. Multiple polysaccharide antigens of group B streptococcus, type Ia: emphasis on sialic acid type specific polysaccharide. Journal of Immunology 1977, 118: 2155–2160.

    Google Scholar 

  14. Jennings, H. J., Katzenellenbogen, E., Lugowski, C., Michon, F., Roy, R., Kasper, D. L. Structure, confrontation and immunology of sialic acid-containing polysaccharides of human pathogenic bacteria. Pure and Applied Chemistry 1984, 56: 893–905.

    Google Scholar 

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Orefici, G., Recchia, S. & Galante, L. Possible virulence marker forStreptococcus agalactiae (Lancefield group B). Eur. J. Clin. Microbiol. Infect. Dis. 7, 302–305 (1988). https://doi.org/10.1007/BF01963108

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  • DOI: https://doi.org/10.1007/BF01963108

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