Bacteriological and serological aspects of group a streptococcal pharyngotonsillitis caused by group a streptococci
- 27 Downloads
Several bacteriological and serological variables were studied in connection with a clinical treatment trial in 212 patients with group A streptococcal pharyngotonsillitis. Anaerobic incubation was not superior to incubation in 5 % CO2 in air for the detection of group A streptococci. Saliva cultures were inferior to conventional throat cultures in detecting group A streptococci. No strains from patients with recurrences were found to be tolerant to penicillin. In several patients (all asymptomatic), group C and G streptococci were found in follow-up cultures. Group A streptococci serology was more often positive after two months than after one month, also in patients without recurrence.
KeywordsInternal Medicine Penicillin Clinical Treatment Treatment Trial Anaerobic Incubation
Unable to display preview. Download preview PDF.
- 1.Gerber, M. A. Diagnosis of pharyngitis: Methodology of throat culture. In: Schulman, S. T. (ed.): Pharyngitis. Management in an era of declining rheumatic fever. Praeger, New York, 1984, p. 61–72.Google Scholar
- 2.Schwartz, R. H., Shulman, S. T. Group C and G streptococci. In-office isolation from children and adolescents with pharyngitis. Clinical Pediatrics 1986, 25: 496–502.Google Scholar
- 3.Stillerman, M., Bernstein, S. H. Streptococcal pharyngitis: evaluation of clinical syndromes in diagnosis. American Journal of Diseases of Children 1961, 101: 476–489.Google Scholar
- 4.Bell, S. M., Smith, D. D. Quantitative throat-swab culture in the diagnosis of streptococcal pharyngitis in children. Lancet 1976, 10: 61–63.Google Scholar
- 5.Ross, P. W. Beta-haemolytic streptococci in saliva. Journal of Hygiene 1971, 69: 347–353.Google Scholar
- 6.Kaplan, E. L., Couser, R., Ballard Huwe, B., Mckay, C., Wannamaker, L. W. Significance of quantitative salivary cultures for group A and non-group A beta-hemolytic streptococci in patients with pharyngitis and in their family contacts. Pediatrics 1979, 64: 904–912.Google Scholar
- 7.Kim, K. S., Kaplan, E. L. Association of penicillin tolerance with failure to eradicate group A streptococci from patients with pharyngitis. Journal of Pediatrics 1985, 107: 681–684.Google Scholar
- 8.Grahn, E., Holm, S. E., Roos, K. Penicillin tolerance in beta-streptococci isolated from patients with streptococcal tonsillitis. Scandinavian Journal of Infectious Diseases 1987, 19: 421–428.Google Scholar
- 9.Smith, T. D., Huskins, W. C., Kim, K. S., Kaplan, E. L. Efficacy of beta-lactamase-resistant penicillin and influence of penicillin tolerance in eradicating streptococci from the pharynx after failure of penicillin therapy for group A streptococcal pharyngitis. Journal of Pediatrics 1987, 110: 777–782.Google Scholar