Skip to main content

Calcitonin: Effect on protein synthesis in different rat tissues

Summary

Protein synthesis was inhibited in the pancreas whereas it was enhanced in the kidney and intestine (jejunumileum) after a single injection of porcine calcitonin (20 MRC units/kg b.wt). The incorporation of [3H]leucine into total protein in the brain, heart, liver and stomach did not change after the hormone treatment.

This is a preview of subscription content, access via your institution.

References

  1. A. M. Nakhla and A. P. N. Majumdar, Biochem. J.170, 445 (1978).

    Google Scholar 

  2. H. D. Becker, S. J. Konturek, D. D. Reeder and J. C. Thompson, Am. J. Physiol.225, 277 (1973).

    Google Scholar 

  3. J. Hotz, H. Goebell and R. Ziegler, Gut18, 615 (1977).

    Google Scholar 

  4. T. K. Gray, P. Brannan, D. Juan, S. G. Morawski and J. S. Fordtran, Gastroenterology71, 392 (1976).

    Google Scholar 

  5. M. W. Walling, T. A. Brasitus and D. V. Kimberg, Gastroenterology73 89 (1977).

    Google Scholar 

  6. G. L. Melson, L. R. Chase and G. D. Aurbach, Endocrinology86, 511 (1970).

    Google Scholar 

  7. A. M. Nakhla and A. Latif, Biochem. J.176, 339 (1978).

    Google Scholar 

  8. R. W. Wannemacher, Jr, W. L. Banks, Jr., and W. H. Wunner, Analyt. Biochem.11, 320 (1965).

    Google Scholar 

  9. A. P. N. Majumdar and A. M. Nakhla, Br. J. Pharmac., in press (1979).

  10. O. H. Lowry, N. J. Rosebrough, A. L. Farr and R. J. Randall, J. biol. Chem.193, 265 (1951).

    Google Scholar 

Download references

Author information

Affiliations

Authors

Additional information

Acknowledgment. This work has been achieved at the Institute of Medical Biochemistry, University of Aarhus, Aarhus, Denmark.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Nakhla, A.M. Calcitonin: Effect on protein synthesis in different rat tissues. Experientia 35, 1525–1526 (1979). https://doi.org/10.1007/BF01962825

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01962825

Keywords

  • Protein Synthesis
  • Total Protein
  • Leucine
  • Calcitonin
  • Hormone Treatment