, Volume 35, Issue 11, pp 1515–1517 | Cite as

PPD-induced blastogenesis is auto-regulated by suppressor cells generated in vitro

  • N. Aoki
  • L. J. Degroot


Suppressor cell induction can be demonstrated during antigen specific blastogenesis by using the same methods which have shown induction of suppressor cells by Con A. Since suppressor cells are rapidly generated during antigen specific blastogenesis, they must regulate the final level of blastogenesis induced during the seven day in vitro incubation.


Suppressor Cell Final Level Cell Induction Suppressor Cell Induction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 2.
    R.K. Gershon, Contemp. top. Immunobiol.3, 1 (1974).Google Scholar
  2. 3.
    T.A. Waldmann and S. Broder, in: Progress in Clinical Immunology, vol. 3, p. 155. Ed. R. Schwartz, Grune and Stratton, New York 1977.Google Scholar
  3. 4.
    L. Shou, S.A. Schwartz and R.A. Good, J. exp. Med.143, 1100 (1976).Google Scholar
  4. 5.
    C. Hubert, G. Delespesse and A. Covaerts, Clin. exp. Immun.26, 95 (1976).Google Scholar
  5. 6.
    J.F.H. Humphrey, J.A. Wands and K.J. Isselbacher, Proc. nat. Acad. Sci. USA75, 1549 (1978).Google Scholar
  6. 7.
    N. Aoki, K.M. Pinnamaneni and L.J. DeGroot, J. clin. Endocr. Metab., in press (1979).Google Scholar
  7. 8.
    T. Hirano and A.A. Nordin, J. Immun.116, 1115 (1976).Google Scholar
  8. 9.
    N.R.S. Sinclair, R.K. Lees, M.E. Wheeler, E.E. Vichos and F.Y. Fung, Cell Immun.27, 153 (1976).Google Scholar
  9. 10.
    F.W. Fitch, H.D. Engers, J.C. Cerottini and K.T. Bruner, J. Immun.116, 716 (1976).Google Scholar
  10. 11.
    J.H. Richard, L.M. Nadler and K.S. Hathcock, J. Immun.119, 961 (1977).Google Scholar
  11. 12.
    A.R. Al-Adra and L.M. Pilaski, Eur. J. Immun.8, 504 (1978).Google Scholar
  12. 13.
    D.D. Eardley and R.K. Gershon, J. Immun.117, 313 (1976).Google Scholar
  13. 14.
    S. Kontiainen and M. Feldmann, Eur. J. Immun.6, 296 (1976).Google Scholar

Copyright information

© Birkhäuser Verlag 1979

Authors and Affiliations

  • N. Aoki
    • 1
    • 2
  • L. J. Degroot
    • 1
    • 2
  1. 1.Department of MedicineKinki University School of MedicineOsaka(Japan)
  2. 2.Department of MedicineUniversity of ChicagoChicagoUSA

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