Abstract
The pathogenic, diagnostic and therapeutic aspects of malakoplakia are reviewed, with special reference to its clinical presentation in women. This presentation varies depending on the site of origin, the extent of the lesions and the predominance of symptoms. Women over 40 years old with a history of recurrent cystitis, occasional self-limiting hematuria and irritative micturition syndrome are identified as a risk group for bladder malakoplakia. The diagnostic approach consists of cystoscopy, cytology and/or biopsy, identifying the characteristic pathological findings: histiocytes with Michaelis-Gutmann bodies. Treatment is based on two criteria: medical, with antibiotics, ascorbic acid and cholinergic agents, and surgical, with extirpation of the plaque by transurethral resection or by open surgery.
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Cózar-Olmo, J.M., Martinez-Piñeiro, J.A., Martinez-Piñeiro, L. et al. Genitourinary malakoplakia in women—A review. Int Urogynecol J 6, 98–102 (1995). https://doi.org/10.1007/BF01962580
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DOI: https://doi.org/10.1007/BF01962580