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Variability of surface-exposed antigens of different strains ofMoraxella catarrhalis

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Abstract

For serological diagnosis of infection withMoraxella (Branhamella) catarrhalis it is important to determine if there is variability of antigenic properties among different strains. Cross-reactions of nine strains were investigated by an immunofluorescence test using sera from immunized rabbits. All titres but one were 1:256 or higher, the highest being 1:4096. Thus a high degree of antigenic similarity was demonstrated among different strains ofMoraxella catarrhalis. However, the homologous titres of six sera were 2 to 16 times higher than the titres for other strains indicating strain variations in antigenic properties of some surface components. There was no correlation between lipopolysaccharide type and titre in the immunofluorescence test.

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Jönsson, I., Holme, T., Krook, A. et al. Variability of surface-exposed antigens of different strains ofMoraxella catarrhalis . Eur. J. Clin. Microbiol. Infect. Dis. 11, 919–922 (1992). https://doi.org/10.1007/BF01962374

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