Prevalence of genital human papillomavirus infections in patients at a sexually transmitted diseases clinic
- 22 Downloads
The human papillomavirus was detected in cervicovaginal cells by the polymerase chain reaction in 14 of 37 (37.8 %) patients attending a sexually transmitted disease (STD) clinic and in 6 of 43 healthy young women (14.0 %) undergoing routine gynecologic examinations who served as controls. The results indicated that even the more malignant types of human papillomaviruses were not uncommon among the control group, and that the prevalence of human papillomavirus infection was significantly higher in STD clinic patients than in the control group. These findings confirm the suggestion that factors other than human papillomavirus infections may be involved in the pathogenesis of cervical cancer.
KeywordsPolymerase Chain Reaction Internal Medicine Cervical Cancer Young Woman Transmitted Disease
Unable to display preview. Download preview PDF.
- 1.zur Hausen H, Schneider A: The role of papillomaviruses in anogenital cancer. In: Salzman NP, Howley PM (ed): The papovaviridae. Plenum Press, New York, 1987, p. 245–263.Google Scholar
- 9.Sato S, Okagaki T, Clark BA, Twiggs LB, Fukushima M, Ostrow RS, Faras AJ: Sensitivity of koilocytosis, immunocytochemistry, and electron microscopy as compared to DNA hybridization in detection HPV in cervical and vaginal condyloma. International Journal of Gynecologic Pathology 1987, 5: 297–307.Google Scholar
- 11.Maniatis T, Fritsch EF, Sambrook J: Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1982, p. 458–459.Google Scholar
- 12.Schneider A, Hotz M, Gissmann L: Increased prevalence of human papillomaviruses in the lower genital tract of pregnant women. International Journal of Cancer 1987, 40: 198–201.Google Scholar
- 13.Kiviat NB, Koutsky LA, Paavonen JA, Galloway DA, Critchlow CW, Beckmann AM, McDougall K, Peterson ML, Stevens CE, Lipinski CM, Holmes KK: Prevalence of genital papillomavirus infection among women attending a college student health clinic or a sexually transmitted disease clinic. Journal of Infectious Diseases 1989, 159: 293–302.PubMedGoogle Scholar