Abstract
An in-house method for costing antibiotic therapy is presented which quantifies hidden costs including costs arising from intravenous administration, labour, serum antibiotic assay, monitoring of haematological and biochemical indices and disposal of sharp instruments. A study of various hospital procedures relating directly to antibiotic therapy was undertaken in an acute medical ward, which involved determination of staff members performing various procedures, consumables used and time taken. Results of this study facilitated accurate quantification of hidden costs of i.v. antibiotic therapy in this ward. Using these results, the cost of five-day courses of gentamicin, cefuroxime, penicillin G, flucloxacillin and erythromycin were calculated. The costing of adverse effects was not attempted. It is recommended that a costing technique of this sort is used in cost-benefit analysis of antibiotic use, as the cost of the drug alone is misleading.
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Davey P, Dodd T, Kerr S, Malek M Audit of IV antibiotic administration. Pharmaceutical Journal 1990, 244: 793–796.
Davey P, Malek M Costs of hospital acquired infection. Pharmaceutical Journal 1991, 246, Supplement: 12–14.
Guglielmo J, Brooks GF Antimicrobial therapy: cost-benefit considerations. Drugs 1989, 38: 473–480.
Eisenberg JM, Koffer H, Glock HA, Connell ML, Loss LE, Talbot GH, Shusterman NH, Strom BL What is the cost of nephrotoxicity associated with aminoglycosides? Annals of Internal Medicine 1987, 107: 900–909.
Davey P, Hernanz C, Lynch W, Malek M, Byrne D Human and non-financial costs of hospital-acquired infection. Journal of Hospital Infection 1991, 18, Supplement A: 79–84.
Daschner F Unnecessary and ecological costs of hospital Infection. Journal of Hospital Infection 1991, 18, Supplement A: 73–78.
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Kerr, J.R., Barr, J.G., Smyth, E.T.M. et al. Technique for calculation of the true costs of antibiotic therapy. Eur. J. Clin. Microbiol. Infect. Dis. 11, 823–827 (1992). https://doi.org/10.1007/BF01960882
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DOI: https://doi.org/10.1007/BF01960882