Evaluation of an enzyme immunoassay for detection ofClostridium difficile toxin A

  • K. Tsimidis
  • A. E. Simor


Internal Medicine Enzyme Immunoassay ofClostridium Difficile 
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  1. 1.
    Bowman RA, Riley TV: Laboratory diagnosis ofClostridium difficile-associated diarrhea. European Journal of Clinical Microbiology and Infectious Diseases 1988, 7: 476–484.Google Scholar
  2. 2.
    Wu TC, Gersch SM: Evaluation of a commercial kit for the routine detection ofClostridium difficile cytotoxin by tissue culture. Journal of Clinical Microbiology 1986, 23: 792–793.PubMedGoogle Scholar
  3. 3.
    Lyerly DM, Lockwood DE, Richardson SH, Wilkins TD: Biological activities of toxins A and B ofClostridium difficile. Infection and Immunity 1982, 35: 1147–1150.PubMedGoogle Scholar
  4. 4.
    Lyerly DM, Krivan HC, Wilkins TD:Clostridium difficile: its disease and toxins. Clinical Microbiology Reviews 1988, 1: 1–18.PubMedGoogle Scholar
  5. 5.
    Taylor NS, Thorne GM, Bartlett JG: Comparison of two toxins produced byClostridium difficile. Infection and Immunity 1981, 34: 1036–1043.PubMedGoogle Scholar
  6. 6.
    Borriello SP, Ketley J, Mitchell J, Barclay FE, Welch AR, Price AB, Stephen J:Clostridium difficile: a spectrum of virulence and analysis of putative virulence determinants in the hamster model of antibiotic-associated colitis. Journal of Medical Microbiology 1987, 24: 53–64.PubMedGoogle Scholar
  7. 7.
    Lyerly DM, Sullivan NM, Wilkins TD: Enzyme-linked immunosorbent assay forClostridium difficile toxin A. Journal of Clinical Microbiology 1983, 17: 72–78.PubMedGoogle Scholar
  8. 8.
    Walker RC, Ruane PJ, Rosenblatt JE, Lyerly DM, Gleaves CA, Smith TF, Pierce PF, Wilkins TD: Comparison of culture, cytotoxicity assays, and enzyme-linked immunosorbent assay for toxin A and toxin B in the diagnosis ofClostridium difficile-related enteric disease. Diagnostic Microbiology and Infectious Diseases 1986, 5: 61–69.Google Scholar
  9. 9.
    Dipersio JR, Varga FJ, Conwell DL, Kraft JA, Kozak KJ, Willis DH: Development of a rapid enzyme immunoassay forClostridium difficile toxin A and its use in the diagnosis ofC. difficile-associated disease. Journal of Clinical Microbiology 1991, 29: 2724–2730.PubMedGoogle Scholar

Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1992

Authors and Affiliations

  • K. Tsimidis
    • 1
  • A. E. Simor
    • 1
  1. 1.Department of Microbiology, Room 602, Mount Sinai Hospital, 600 University AvenueUniversity of TorontoTorontoCanada

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