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Recent observations on the structure and the properties of yeast NMN adenylyltransferase

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Summary

A homogeneous preparation of yeast NMN adenylyltransferase (EC 2.7.7.1) showed microheterogeneity, which was revealed by FPLC (Fast Protein Liquid Chromatography) ion exchange chromatography. The resolved components have been characterized with respect to electrophoretic behavior and adenine content. The results led to a hypothesis about a possible role of poly(ADP-ribosylation) in modulating the enzyme activity.

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Authors and Affiliations

  1. Dipartimento di Biologia Cellulare, Università di Camerino, I-62032, Camerino, Italy

    S. Ruggieri, L. Gregori & P. Natalmi

  2. Istituto di Biochimica, Università di Ancona, I-60100, Ancona, Italy

    A. Vita & G. Magni

Authors
  1. S. Ruggieri
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  2. L. Gregori
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  3. P. Natalmi
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  4. A. Vita
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  5. G. Magni
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Ruggieri, S., Gregori, L., Natalmi, P. et al. Recent observations on the structure and the properties of yeast NMN adenylyltransferase. Experientia 44, 27–29 (1988). https://doi.org/10.1007/BF01960232

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  • DOI: https://doi.org/10.1007/BF01960232

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