Experientia

, Volume 47, Issue 5, pp 454–457 | Cite as

Age-related lipid peroxidation in the digestive gland of mussels: The role of the antioxidant defence systems

  • A. Viarengo
  • L. Canesi
  • M. Pertica
  • D. R. Livingstone
  • M. Orunesu
Research Articles

Summary

The main cellular defence systems against free radical-mediated oxidative stress are significantly reduced in the dige+ive gland of aged (>10 years old) compared to younger (2–4 years old) mussels (Mytilus edulis L.). Moreover, the concentration of lipid peroxidation products (malondialdehyde) is increased in the same age group with respect to younger animals. The obtained data indicate that an impairment of the antioxidant defence systems would render the older animals more susceptible to peroxidative stress, thus supporting the general significance of the free radical theory of aging.

Key words

aging mussels free radicals antioxidant systems lipid peroxidation 

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Copyright information

© Birkhäuser Verlag 1991

Authors and Affiliations

  • A. Viarengo
    • 1
  • L. Canesi
    • 1
  • M. Pertica
    • 2
  • D. R. Livingstone
    • 1
  • M. Orunesu
    • 1
  1. 1.Istituto di Fisiologia GeneraleUniversità di GenovaGenovaItaly
  2. 2.Plymouth Marine LaboratoryPlymouthEngland

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