Advertisement

Experientia

, Volume 37, Issue 4, pp 387–389 | Cite as

The effect of splenectomy on the development of experimental pyelonephritis

  • M. Güngör
  • Ö. Anĝ
  • D. İnanç
  • İ. Petorak
  • H. Koyuncuoĝlu
Article

Summary

Although an unusually high incidence of a variety of infections in infants who had undergone splenectomy has been reported by a number of investigators the subject remains somewhat controversial. In the present experiments the role of the spleen in the protection of rats against experimentally induced hematogenous pyelonephritis was studied. The results of this study suggest that the spleen has an important preventive function against bacterial infection.

Keywords

Present Experiment Bacterial Infection Pyelonephritis Preventive Function Experimental Pyelonephritis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    R. Grofstein and S. S. Gellis, Am. J. Dis. Child.91, 566 (1956).Google Scholar
  2. 2.
    A. J. Eraklis and R. M. Filler, J. Pediat. Surg.7, 382 (1972).PubMedGoogle Scholar
  3. 3.
    H. King and M. G. Shumacker, Ann. Surg.136, 239 (1952).PubMedGoogle Scholar
  4. 4.
    W. H. Crosby and N. R. Benjamin, J. Path.39, 119 (1961).Google Scholar
  5. 5.
    E. F. Ellis and R. T. Smith, Pediatrics37, 111 (1966).PubMedGoogle Scholar
  6. 6.
    H. R. Shinefield, C. R. Steinberg and D. Kaye, J. exp. Med.123, 777 (1966).PubMedGoogle Scholar
  7. 7.
    V. V. Likhite, Nature253, 742 (1975).PubMedGoogle Scholar
  8. 8.
    H. Rothberg and L. A. Corallo, Proc. Soc. exp. Biol. Med.100, 220 (1959).PubMedGoogle Scholar
  9. 9.
    A. Öbek, Ö. Anĝ, İ. Petorak, A. İplikçi, E. Büget, L. Eroĝlu and M. Güngör, Chemotherapy19, 171 (1973).PubMedGoogle Scholar
  10. 10.
    A. Öbek, Z. Güvener, L. Eroĝlu, M. Güngör and M. Yurtkuran, Chemotherapy21, 67 (1975).PubMedGoogle Scholar
  11. 11.
    İ. Petorak, A. İplikçi, A. Öbek, Ö. Anĝ and E. Büget, Exp. Path.12, 174 (1976).Google Scholar
  12. 12.
    M. M. Zatz and E. M. Lance, J. exp. Med.134, 224 (1971).PubMedGoogle Scholar
  13. 13.
    N. R. St. C. Sinclair and E. V. Elliott, J. Immun.101, 251 (1968).PubMedGoogle Scholar
  14. 14.
    A. Constantopoulos, V. A. Najjar, S. B. Wish, T. H. Necheles and L. L. Stolbach, Am. J. Dis. Child125, 663 (1973).PubMedGoogle Scholar
  15. 15.
    J. R. Batisto, L. C. Cantor, F. Bosek, A. L. Goldstein and E. Canberra, Nature222, 1197 (1969).Google Scholar

Copyright information

© Birkhäuser Verlag 1981

Authors and Affiliations

  • M. Güngör
    • 1
  • Ö. Anĝ
    • 1
  • D. İnanç
    • 1
  • İ. Petorak
    • 1
  • H. Koyuncuoĝlu
    • 1
  1. 1.Department of Pharmacology and Clinical Pharmacology, Department of Microbiology, Parasitology and Tropical Diseases, and Department of Histology and Embryology of Istanbul Medical FacultyIstanbulTurkey

Personalised recommendations