, Volume 37, Issue 4, pp 387–389 | Cite as

The effect of splenectomy on the development of experimental pyelonephritis

  • M. Güngör
  • Ö. Anĝ
  • D. İnanç
  • İ. Petorak
  • H. Koyuncuoĝlu


Although an unusually high incidence of a variety of infections in infants who had undergone splenectomy has been reported by a number of investigators the subject remains somewhat controversial. In the present experiments the role of the spleen in the protection of rats against experimentally induced hematogenous pyelonephritis was studied. The results of this study suggest that the spleen has an important preventive function against bacterial infection.


Present Experiment Bacterial Infection Pyelonephritis Preventive Function Experimental Pyelonephritis 
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Copyright information

© Birkhäuser Verlag 1981

Authors and Affiliations

  • M. Güngör
    • 1
  • Ö. Anĝ
    • 1
  • D. İnanç
    • 1
  • İ. Petorak
    • 1
  • H. Koyuncuoĝlu
    • 1
  1. 1.Department of Pharmacology and Clinical Pharmacology, Department of Microbiology, Parasitology and Tropical Diseases, and Department of Histology and Embryology of Istanbul Medical FacultyIstanbulTurkey

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