, Volume 40, Issue 1, pp 112–114 | Cite as

Acute changes in dopamine metabolism in the medio-basal hypothalamus following adrenalectomy

  • D. H. G. Versteeg
  • I. Van Zoest
  • E. R. De Kloet


During the first hour following adrenalectomy the α-MPT-induced disappearance of dopamine was increased in the arcuate nucleus compared to that in sham-operated rats. In a number of other brain regions of both adrenalectomized and sham-adrenalectomized rats only stress-induced changes were observed in catecholamine utilization. These data suggest that corticosterone selectively modulates dopamine utilization in the medio-basal hypothalamus.


Dopamine Brain Region Catecholamine Corticosterone Arcuate Nucleus 
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Copyright information

© Birkhäuser Verlag Basel 1984

Authors and Affiliations

  • D. H. G. Versteeg
    • 1
  • I. Van Zoest
    • 1
  • E. R. De Kloet
    • 1
  1. 1.Rudolf Magnus Institute for Pharmacology, Medical FacultyUniversity of UtrechtUtrecht(The Netherlands)

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