Experientia

, Volume 44, Issue 6, pp 506–508 | Cite as

Massive striatal dopamine release in acute cerebral ischemia in rats

  • H. Yao
  • S. Sadoshima
  • T. Ishitsuka
  • T. Nagao
  • M. Fujishima
  • T. Tsutsumi
  • H. Uchimura
Short Communications

Summary

Extracellular dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and cerebral blood flow were simultaneously determined using in vivo brain dialysis and a hydrogen clearance method in the striatum of spontaneously hypertensive rats during ischemia and after recirculation. Massive striatal dopamine release was demonstrated in acutely induced ischemic brain.

Key words

Dopamine release cerebral ischemia striatum in vivo brain dialysis spontaneously hypertensive rats 

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Copyright information

© Birkhäuser Verlag Basel 1988

Authors and Affiliations

  • H. Yao
    • 1
  • S. Sadoshima
    • 1
  • T. Ishitsuka
    • 1
  • T. Nagao
    • 1
  • M. Fujishima
    • 1
  • T. Tsutsumi
    • 2
  • H. Uchimura
    • 2
  1. 1.The Second Department of Internal Medicine, Faculty of MedicineKyushu UniversityFukuoka CityJapan
  2. 2.Center for Emotional and Behavioral DisordersHizen National Mental HospitalSagaJapan

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