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Effect of oestradiol on RNA polymerase of foetal guinea-pig uterus

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Summary

The administration of 10 μg oestradiol to the foetus of the guinea-pig (55–65 days of gestation) causes an increase in RNA polymerase I and II activities in the nuclei of the foetal uterus. RNA polymerase I activity increased by 4 times above the control values after 120 min (p<0.001) whereas RNA polymerase II activity increased more rapidly, reaching 2.5 times the control levels at 30 min and 4 times by 120 min after treatment (p<0.01).

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Authors and Affiliations

  1. C.N.R.S. Steroid Hormone Research Unit, Foundation for Hormone Research, 26 boulevard Brune, F-75014, Paris, France

    F. Laure & J. R. Pasqualini

Authors
  1. F. Laure
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  2. J. R. Pasqualini
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Laure, F., Pasqualini, J.R. Effect of oestradiol on RNA polymerase of foetal guinea-pig uterus. Experientia 39, 209–210 (1983). https://doi.org/10.1007/BF01958905

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  • DOI: https://doi.org/10.1007/BF01958905

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