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Experientia

, Volume 39, Issue 2, pp 196–198 | Cite as

Allophenic mice produced from embryos aggregated with antibody

  • J. Palmer
  • M. J. Dewey
Article

Summary

One difficulty in the production of allophenic mice by aggregation of preimplantation embryos is that they frequently roll apart before the bonds between the blastomeres have had time to form. One solution to the problem, described here, is to pretreat one of the embryos with rabbit anti-mouse serum just prior to pushing them together. Blastocyst formation is unhampered by antibody treatment, and numerous allophenic mice have already been produced with this new procedure.

Keywords

Antibody Treatment Preimplantation Embryo Blastocyst Formation Allophenic Mouse 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1983

Authors and Affiliations

  • J. Palmer
    • 1
  • M. J. Dewey
    • 1
  1. 1.Department of BiologyUniversity of South CarolinaColumbiaUSA

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