Summary
During antifungal screening of products from higher plants 1,3,7-trimethylxanthine (caffeine), isolated from the seeds ofCoffea arabica, was found to exhibit strong fungitoxicity. The fungicidal ability of caffeine has been tested in vitro on 4 fish pathogenic species of Saprolegniaceae. The applicability of this chemical has also been tested by conducting tolerance tests, usingColisa lalia andPuntius sophore as test-fishes. The present studies have established that caffeine is a potential fish fungicide.
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Acknowledgment. The help rendered by Dr K. Rastogi and Dr R. Singh, Central Drug Research Institute, Lucknow, for spectroscopic analysis is gratefully acknowledged. The senior author is thankful to Sri S. P. Singh, and to Dr S. B. Singh, Department of Botany, U.N. Postgraduate College, Padrauna, for encouragement. thanks are also due to Dr S. Mekrani for his help in various ways.
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Prabhuji, S.K., Srivastava, G.C., Rizvi, S.J.H. et al. 1,3,7-Trimethylxanthine (caffeine); a new natural fish fungicide. Experientia 39, 177–179 (1983). https://doi.org/10.1007/BF01958886
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DOI: https://doi.org/10.1007/BF01958886