Summary
Oral administration of a 70% solution of sucrose to starved adult rats resulted 1 h after feeding in a 3.5-fold stimulation of intestinal chromatin template activity assayed in vitro usingE. coli RNA polymerase. A similar stimulatory effect was observed with fructose, whereas glucose exhibited a weaker effect, indicating that the nature of the ingested carbohydrate may have a direct effect on the extent of intestinal chromatin template activation.
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The authors like to thank F. Gossé and M. Galluser for excellent technical assistance. This work was supported by DGRST grant No. 81L 1312.
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Raul, F., Launay, J.F. Stimulation of intestinal chromatin template activity by dietary carbohydrates in adult rats. Experientia 39, 166–167 (1983). https://doi.org/10.1007/BF01958879
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DOI: https://doi.org/10.1007/BF01958879