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Experientia

, Volume 39, Issue 2, pp 149–151 | Cite as

Influence of the enteric surface coat on the unidirectional flux of acetamide across the wall of rat small intestine

  • G. Esposito
  • A. Faelli
  • M. Tosco
  • M. N. Orsenigo
  • R. De Gasperi
  • N. Pacces
Article

Summary

In vivo treatment of the jejunal mucosa with glycosidic enzymes seems to remove the enteric surface coat of the enterocyte. As a consequence, the mucosa-to-serosa unidirectional flux of acetamide increases remarkably. The glycocalyx probably represents a barrier to the diffusion of small hydrosoluble solutes.

Keywords

Enzyme Small Intestine Acetamide Surface Coat Jejunal Mucosa 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1983

Authors and Affiliations

  • G. Esposito
    • 1
    • 2
    • 3
  • A. Faelli
    • 1
    • 2
    • 3
  • M. Tosco
    • 1
    • 2
    • 3
  • M. N. Orsenigo
    • 1
    • 2
    • 3
  • R. De Gasperi
    • 1
    • 2
    • 3
  • N. Pacces
    • 1
    • 2
    • 3
  1. 1.Sezione di Fisiologia Generale e Chimica Biologica dell'Università di MilanoFacoltà di FarmaciaMilano(Italy)
  2. 2.Dipartimento di Fisiologia e Biochimica GeneraliFacoltà di ScienzeMilano(Italy)
  3. 3.Dipartimento di BiologiaFacoltà di ScienzeMilano(Italy)

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